منابع مشابه
Dev108712 2543..2548
Interest in the amyloid precursor protein (APP) has increased in recent years due to its involvement in Alzheimer’s disease. Since its molecular cloning, significant genetic and biochemical work has focused on the role of APP in the pathogenesis of this disease. Thus far, however, these studies have failed to deliver successful therapies. This suggests that understanding the basic biology of AP...
متن کاملRevista GED04 Dez 2011-B.indd
Morbid obesity is an increasingly common problem worldwide6, and therefore, there is increasing utilization of surgical procedures for the treatment of this disease5. One of the preferred techniques is the Roux-en-Y gastric bypass. This technique which generally leads to rapid weight loss is associated with the formation of biliary calculi and consequently to its complications (e.g., acute panc...
متن کاملN1,N12-Diacetylspermine as a Blood Based Lung Cancer Biomarker
It is becoming well recognized that metabolic perturbations are inherent hallmarks of tumorigenesis [1,2]. Metabolites represent the functional products of cellular processes, which are highly responsive to both pathological and environmental stimuli. As such, metabolites are the closest representation of an individual’s current physiological state. Therefore, exploration of metabolic alteratio...
متن کاملLeptin--2548 g/A polymorphism in endometrial cancer.
BACKGROUND Previously, the polymorphism-2548 G/A within the promoter of the leptin (LEP) gene was reported to be associated with overweight and obesity, the factors significantly associated to increased endometrial cancer risk. Leptin has been described to play an important role in signal transduction in endometrial cancer cells indicating that leptin promotes endometrial cancer growth and inva...
متن کاملReservoir Operating by Ant Colony Optimization for Continuous Domains (ACOR) Case Study: Dez Reservoir
A direct search approach to determine optimal reservoir operating is proposed with ant colony optimization for continuous domains (ACOR). The model is applied to a system of single reservoir to determine the optimum releases during 42 years of monthly steps. A disadvantage of ant colony based methods and the ACOR in particular, refers to great amount of computer run time consumption. In this st...
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ژورنال
عنوان ژورنال: Ciência Rural
سال: 2011
ISSN: 0103-8478
DOI: 10.1590/s0103-84782011000200031